Thyrotropin-Binding Inhibitory Immunoglobulin (TBII), Blood

This lab test is useful for the diagnosis and management of Graves’ disease, neonatal hypothyroidism and postpartum thyroid dysfunction.

In certain instances, the body makes antibodies which can attack the thyroid gland, leading to chronic inflammation causing it to be dysfunctional. The thyroid gland is responsible for the production and release of two principal hormones called T3 and T4. TSH comes from the pituitary gland to the thyroid to stimulate the production of these hormones. It binds to a protein molecule and the antibodies produced against it is called thyroid binding inhibitory immunoglobulin (TBII). When TBII is produced, it slows down T3 and T4 production, and the patient eventually becomes hypothyroid.

This test is performed in following conditions such as:

Signs and symptoms of hypothyroidism
• Weight gain
• Dry skin
• Constipation
• Cold intolerance
• Fatigue and weakness

Also Known As: TSH Receptor Blocking Antibody