This test measures the porphyrins in the feces to make a diagnosis of porphyria, a group of disorders categorized by enzyme deficiencies in the heme synthesis pathway. Heme is the iron-containing pigment that is found in hemoglobin and other proteins. During the synthesis of heme, by-products called porphyrins are produced. These are normally in a low level and are excreted in the feces. During the heme synthesis pathway, if any of the enzymes are deficient, there is a build-up of some of the by-products like uroporphyrin and coproporphyrin. Since there is more than one type of porphyria, measuring porphyrins level both in urine and feces is needed to differentiate between the types of disease.
This test is performed in following conditions such as:
• Acute attacks triggered by a variety of drugs or environmental factors
• Abdominal pain, nausea
• Peripheral neuropathy
• Muscle weakness
• Urinary retention
• Blisters, Scarring, Hyperpigmentation
• Redness, Itching, Burning
Also Known As: Coproporphyrin, Uroporphyrin
It may be necessary to discontinue certain medications which may impact the results of this Porphyrins Test. Please check with your doctor to determine if you are taking any medications which may affect this test.
Estimated Time Taken
Turnaround for this test is typically 4-12 business days.