Iron and Total Iron-binding Capacity

Iron (Fe) and total iron-binding capacity (TIBC) are both tests used in iron studies. Iron is transported in the body by a transporter protein called transferrin. TIBC is a measure of the amount of transferrin available which is capable of transporting iron. TIBC is a good test used to measure the total amount of iron that can possibly be carried around the body. This test, in combination with a serum iron test, is used to determine patients who have either iron deficiency or iron overload. In iron deficiency, the TIBC will be raised with a low iron level, and in iron overload, the iron level is very high and the TIBC is normal or low.

This test is performed in following conditions such as:

• Chronic fatigue/tiredness
• Dizziness
• Weakness
• Headaches
• Pallor
• Symptoms of iron overload

Also Known As: TIBC, transferrin saturation, Unsaturated Iron-binding Capacity (UIBC)