Fibrinogen Activity

Fibrinogen is essential for the formation of a blood clot. Deficiency can produce mild to severe bleeding disorders.

Fibrinogen is a protein that is made in the liver and circulates in the blood. It is one of the coagulation factors that is part of the coagulation cascade, and event that is important for the proper formation of blood clots. Fibrinogen is a soluble protein that responds to other clotting factors and blood vessel injury by converting to insoluble fibrin which crosslink to make a meshwork that forms the blood clot. A fibrinogen activity test is a blood test that is used in order to determine how well the fibrinogen works in helping to make a blood clot. It is used to diagnose bleeding disorders.

This test is performed in following conditions such as:

• Unexplained or prolonged bleeding
• Thrombosis
• Abnormal PT and PTT test result
• Symptoms of abnormal fibrinolysis
• Coagulation factor deficiency or dysfunction
• Long-term anticoagulation medication e.g. warfarin, clopidogrel

Also Known As: Clottable Fibrinogen