Estrone

Estrone is primarily derived from metabolism of androstenedione in peripheral tissues, especially adipose tissues. Individuals with obesity have increased conversion of androstenedione to Estrone leading to higher concentrations. In addition, an increase in the ratio of Estrone to Estradiol may be useful in assessing menopause in women.

Estrogens are a group of steroid hormones that are converted from androgens and are responsible for the development of the secondary sexual characteristics and the functioning of the reproductive organs. Estrogens can be used to diagnose a host of disorders in women depending on the phase of life they are in. There are 3 different types of estrogens that can be measured. This test measures estrone in the blood. Estrone is primary estrogen that is produced in post-menopausal women and in men.

This test is performed in following conditions such as:

• Girls experiencing signs of early or late puberty
• Women experiencing infertility issues
• Women on hormone replacement therapy in menopause
• To assess ovarian function
• In women with irregular menstrual periods
• Symptoms of menopause
• Men with signs of testosterone deficiency

Also Known As: E1