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Quest Diagnostics Test Code: 8474

Primary infection by EBV causes infectious mononucleosis, usually a self-limiting disease in children and young adults. Infection with EBV can cause lymphoproliferative disorders including tumors. Absence of VCA-IgG usually indicates the patient is susceptible to EBV infection.

Epstein-Barr Virus (EBV) is a virus that is responsible for the disease mononucleosis. It causes mild to moderate infection and is quite common amongst the adult population. Most people do not experience symptoms, but in some instances can get very ill. There are different tests which can be performed for the detection of EBV. The viral capsid antigen IgG antibodies against EBV start to rise after several weeks of initial infection. At a point when the infection has been resolved, the level of IgG antibodies plateaus, providing the host with lifelong immunity to EBV. IgG, along with IgM are useful in determining whether there is active EBV disease or if there was previous exposure to the virus.

This test is performed in following conditions such as:

• Fatigue
• Fever
• Lack of appetite
• Rash
• Sore throat
• Swollen glands in the neck
• Weakness and sore muscles

Also Known As: Epstein Barr Viral Capsid Antigen Antibodies IgG


IgG antibodies will typically be detectable around 2-4 weeks after exposure and will remain detectable for the rest of a person's life. In some people they may be detectable sooner.


Specimen Collected
  • Blood
Estimated Time Taken

Turnaround time for the EBV Abs VCA, IgG is typically 2-3 business days.