Antimullerian Hormone

AMH/MIS may be used in the investigation of ovarian reserve and the perimenopausal transition in women; the detection and onset of puberty in the young, the differential diagnosis of intersex disorders; the diagnosis of cryptorchidism and anorchidism, and the evaluation of male gonadal function in all ages.

Anti-Müllerian hormone (AMH), also known as Müllerian-inhibiting hormone, is a hormone which is responsible for sexual differentiation and folliculogenesis. In developing fetuses, production of AMH suppresses the development of female sex organs, and therefore, a male child develops. AMH can be used to discover the cause of intersex babies, as well as the cause for cryptorchidism and anorchidism. It is also produced by cells that surround follicles which are found in the ovaries. As such, AMH is produced in women until menopause when there are no longer any eggs in the ovaries. Because of this, AMH is used as a test to indicate ovarian reserve, and is indirectly a marker of fertility in pre-menopausal women. This is an important test to indicate whether infertility problems are due to a lack of eggs or due to another problem.

This test is performed in following conditions such as:

• Struggle to get pregnant for longer than a year
• Have someone in the family who was infertile
• Older and still want children
• Planning on getting IVF
• Getting chemo- or radiotherapy which could cause infertility

Also Known As: AMH