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Quest Diagnostics Test Code: 227

Aldolase aids in the diagnosis of primary disease of skeletal muscle myocardial infarction and viral hepatitis.

Aldolase is an enzyme that is found throughout the body. In order to have energy for metabolic processes in the body, glucose needs to be broken down. This is a long process with many steps, but one of the most important enzymes that aids in this reaction is aldolase. Therefore, aldolase is found in high concentration in skeletal muscles and in the liver where a large amount of energy is needed. When serum aldolase levels are increased, it is usually a sign of severe muscle or liver damage. When muscle and liver cells get damaged, they release aldolase into the bloodstream which can be measured. It is useful for detecting heart attacks, cirrhosis and hepatocellular carcinoma.

This test is performed in following conditions such as:

• Chest pain
• Jaundice
• A significant drinking history
• Pain in the abdomen on the right upper side
• Muscle weakness
• Muscle pain


Specimen Collected
  • Blood
Estimated Time Taken

Turnaround time for this test is typically 1-2 business days.